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1.5 billionth tablet for the treatment of schistosomiasis

28. January 2022
in News, Pharmaceuticals, Processing Technologies

Ergoya Gebre is the deputy head of the Mizan health centre, culturally an unusually senior position for such a young woman. Bench Maji, Ethiopia.

Photograph: Marcus Perkins for Merck KGaA Individual release: Model release sheet 11 in the permissions PDF. Local release signed by a school headmaster, community leader or zonal health head: Model release sheet 21 in the permissions PDF. Global Permission across Bench Maji: Invited to work in Ethiopia by the Ethiopian Federal Ministry of Health, a Photography permit was issued by the Federal Democratic Republic of Ethiopia Broadcasting Authority to photograph the schistosomiasis story in Bench Maji. (See pages 1 to 7 of the permissions PDF).

As part of its part­ner­ship with the World Health Orga­ni­za­tion (WHO), Mer­ck, a sci­ence and tech­nol­o­gy com­pa­ny, has donat­ed its 1.5 bil­lionth tablet of praz­i­quan­tel. The drug is the treat­ment of choice for schis­to­so­mi­a­sis (also known as bil­harzia) — one of the most com­mon and dev­as­tat­ing par­a­sitic dis­eases in trop­i­cal coun­tries. Chil­dren in poor and rur­al com­mu­ni­ties are par­tic­u­lar­ly hard hit. Since 2007, Mer­ck has pro­vid­ed treat­ment for more than 600 mil­lion school chil­dren in 47 coun­tries in sub-Saha­ran Africa and beyond.

“The dona­tion of the 1.5 bil­lionth praz­i­quan­tel tablet is a sig­nif­i­cant mile­stone in our col­lab­o­ra­tive com­mit­ment to erad­i­cate schis­to­so­mi­a­sis. To date, hun­dreds of mil­lions of chil­dren who oth­er­wise would not have received treat­ment have been able to receive treat­ment for this dev­as­tat­ing dis­ease. A study pub­lished in the jour­nal The Lancet Infec­tious Dis­eases demon­strates the sig­nif­i­cant impact of our dona­tion pro­gram. Accord­ing to the study, the preva­lence of schis­to­so­mi­a­sis in school-age chil­dren in sub-Saha­ran Africa has been reduced by near­ly 60% over the past 20 years. I am very proud of our com­pa­ny’s con­tri­bu­tion to the fight against schis­to­so­mi­a­sis. We will con­tin­ue our full com­mit­ment until the dis­ease is erad­i­cat­ed for good.”

- Peter Guenter, Mem­ber of the Exec­u­tive Board

The pro­gram to fight schis­to­so­mi­a­sis is a key com­po­nent of Mer­ck­’s cor­po­rate goal to improve the qual­i­ty of life, health and well-being for more and more peo­ple around the world. The 1.5‑billionth tablet was part of a 24-mil­lion-tablet ship­ment to the Demo­c­ra­t­ic Repub­lic of Con­go. Since 2013, the cen­tral African coun­try has received more than 138 mil­lion tablets.

At the same time as the praz­i­quan­tel ship­ment to the Demo­c­ra­t­ic Repub­lic of Con­go, the com­pa­ny is expand­ing its com­mit­ment to Rwan­da. In Jan­u­ary 2021, the com­pa­ny had announced plans to pro­vide the coun­try with 8 mil­lion tablets annu­al­ly for the treat­ment of adult schis­to­so­mi­a­sis patients. This addi­tion­al quan­ti­ty com­ple­ments the annu­al tablet dona­tion for the treat­ment of school-aged chil­dren. The first ship­ment arrived in the coun­try in late 2021. Since then, the first adults have already been treat­ed, mark­ing the offi­cial start of the part­ner­ship. The treat­ment is a key com­po­nent of the Gov­ern­ment of Rwan­da’s strate­gic plan to elim­i­nate schis­to­so­mi­a­sis and oth­er NTDs as a pub­lic health bur­den by 2024.

The Group’s schis­to­so­mi­a­sis pro­gram address­es the key require­ment for treat­ment with praz­i­quan­tel as an inte­gral part of the WHO’s 2021–2030 Roadmap for Neglect­ed Trop­i­cal Dis­eases. The com­pa­ny also con­tributes to the Unit­ed Nations (UN) Sus­tain­able Devel­op­ment Goals (SDGs), specif­i­cal­ly Health and Well­be­ing (Goal 3) and Part­ner­ships (Goal 17). This is in line with the sus­tain­abil­i­ty strategy.

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