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Home Focus Pharmaceuticals

Confident Particle and Molecule Analysis

2. November 2018
in Pharmaceuticals
The new Zetasizer Pro and Ultra light-scattering solutions for revolutionary nanoparticle and molecule analysis. Picture: Malvern Panalytical

The new Zetasizer Pro and Ultra light-scattering solutions for revolutionary nanoparticle and molecule analysis. (Picture: Malvern Panalytical)

 
Malvern Pan­a­lyt­i­cal has unveiled its new Zeta­siz­er Pro and Ultra sys­tems, designed to increase con­fi­dence in deci­sion-mak­ing with­in key ana­lyt­i­cal work­flows asso­ci­at­ed with prod­uct devel­op­ment and qual­i­ty con­trol. Built on the her­itage of the mar­ket-lead­ing Zeta­siz­er Nano range, and already the proud recip­i­ents of a Red Dot 2018 design award, these new flag­ship instru­ments deliv­er sig­nif­i­cant improve­ments in the qual­i­ty and speed of par­ti­cle size, mol­e­cule size and zeta poten­tial mea­sure­ments, using the tech­niques of dynam­ic and elec­trophoret­ic light scattering.
The Zeta­siz­er Pro and Ultra sys­tems are con­trolled by ground­break­ing ZS Xplor­er soft­ware, intro­duc­ing new sam­ple-cen­tric work­flows which make method design and data analy­sis more straight­for­ward for new users, while pre­serv­ing full acces­si­bil­i­ty for users expe­ri­enced in the appli­ca­tion of light scat­ter­ing meth­ods. New analy­sis capa­bil­i­ties answer, for the first time, key issues asso­ci­at­ed with the pres­ence of dust or aggre­gates when apply­ing dynam­ic light scat­ter­ing for par­ti­cle and mol­e­c­u­lar char­ac­ter­i­za­tion, fil­ter­ing these from the results to give a truer over­all pic­ture of the sam­ple. This is sup­port­ed by inte­grat­ed, deep-learn­ing empow­ered data qual­i­ty guid­ance, offer­ing the user instant feed­back on their results and pro­vid­ing action­able advice on how to improve poor qual­i­ty data.
A key dif­fer­en­tia­tor of the Zeta­siz­er Ultra is its patent­ed Mul­ti-Angle Dynam­ic Light Scat­ter­ing (MADLS) tech­nol­o­gy, which auto­mates mul­ti­ple-angle size mea­sure­ments, pro­vid­ing high­er res­o­lu­tion and more com­plete par­ti­cle size dis­tri­b­u­tions. MADLS also enables cal­i­bra­tion-free par­ti­cle con­cen­tra­tion analy­sis for a wide range of mate­ri­als, resolv­ing the indi­vid­ual con­cen­tra­tions of dif­fer­ent size pop­u­la­tions. The new dis­pos­able cap­il­lary siz­ing cell pro­vides the ulti­mate in non-destruc­tive, low vol­ume (3 μL) analy­sis, extend­ing the upper range to 10 μm and deliv­er­ing high qual­i­ty data whilst reduc­ing cost. The Zeta­siz­er Ultra’s speed and ease-of-use are uncom­pro­mised by these unique and pow­er­ful capa­bil­i­ties, mak­ing it the most advanced light scat­ter­ing sys­tem available.

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