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This year’s research prize goes to Austria

11. July 2019
in News
ADC Bio secures additional equity round investment

In 2019, the Ham­burg life sci­ence com­pa­ny is pre­sent­ing its high­ly pres­ti­gious research prize for the 24th time. The inde­pen­dent Eppen­dorf Award Jury chaired by Prof. Rein­hard Jahn select­ed Dr. Georg Win­ter, Prin­ci­pal Inves­ti­ga­tor at the CeMM Research Cen­ter for Mol­e­c­u­lar Med­i­cine of the Aus­tri­an Acad­e­my of Sci­ences, Vien­na, Aus­tria, as the 2019 win­ner of the Eppen­dorf Award for Young Euro­pean Investigators.

The Award cer­e­mo­ny took place at the EMBL Advanced Train­ing Cen­tre in Hei­del­berg, Ger­many, on June 27, 2019. The lau­da­tio hon­or­ing Georg Winter’s achieve­ments was held by Award Jury Chair­man Prof. Rein­hard Jahn of the Max Planck Insti­tute for Bio­phys­i­cal Chem­istry, Göttingen.

Georg Win­ter, born 1985, receives the € 20,000 prize for his pio­neer­ing work devel­op­ing a method for tar­get­ing spe­cif­ic pro­teins for degra­da­tion using het­er­ob­i­func­tion­al chem­i­cal com­pounds to specif­i­cal­ly recruit ubiq­ui­tin E3 lig­as­es to the intend­ed pro­tein tar­get for destruction.

The Jury: “This pow­er­ful sys­tem enables tar­get­ing of pre­vi­ous­ly undrug­gable tar­gets and shows promise both in cells and in vivo in mod­el sys­tems as an emerg­ing ther­a­py.” Georg Winter’s work has led to a fury of excite­ment across phar­ma­ceu­ti­cal com­pa­nies and has result­ed in sev­er­al patents; it holds promise to yield nov­el ther­a­pies for can­cer and oth­er dis­eases of unmet need.

“I felt incred­i­bly hon­ored and hum­bled when I learned that I will be award­ed with the 2019 Eppen­dorf Award. This price rec­og­nizes our work in inno­vat­ing a gen­er­al­iz­able solu­tion to tar­get­ed pro­tein degra­da­tion in vivo. We are pur­su­ing this new ther­a­peu­tic par­a­digm towards our ulti­mate goal of degrad­ing dis­ease-rel­e­vant pro­teins that are thus far deemed ‘undrug­gable’. My con­tri­bu­tion to this excit­ing field would not have been pos­si­ble with­out ground­break­ing work from esteemed peers, the amaz­ing sup­port from men­tors, and close and fruit­ful col­lab­o­ra­tions with col­leagues in the lab.”

Georg Win­ter, Prin­ci­pal Inves­ti­ga­tor at the CeMM Research Cen­ter for Mol­e­c­u­lar Med­i­cine of the Aus­tri­an Acad­e­my of Sciences

With the Eppen­dorf Award for Young Euro­pean Inves­ti­ga­tors, which was estab­lished in 1995, Eppen­dorf AG hon­ors out­stand­ing work in bio­med­ical research and sup­ports young sci­en­tists in Europe up to the age of 35. The Eppen­dorf Award is pre­sent­ed in part­ner­ship with the sci­en­tif­ic jour­nal Nature. The Award win­ner is select­ed by an inde­pen­dent com­mit­tee com­posed of Prof. Rein­hard Jahn (Max Planck Insti­tute for Bio­phys­i­cal Chem­istry, Göt­tin­gen, Ger­many), Prof. Dieter Häussinger (Clin­ic for Gas­troen­terol­o­gy, Hepa­tol­ogy and Infec­ti­ol­o­gy, Düs­sel­dorf, Ger­many), Prof. Maria Lep­tin (EMBO, Hei­del­berg, Ger­many), Prof. Mar­tin J. Lohse (Max Del­brück Cen­ter for Mol­e­c­u­lar Med­i­cine in the Helmholtz Asso­ci­a­tion, Berlin, Ger­many), and Prof. Lau­ra Mach­esky (Can­cer Research UK Beat­son Insti­tute, Glas­gow, UK).

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